Preparation for Child Psych PRITE and Boards
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Introduction

  • Selective serotonin reuptake inhibitors (SSRIs) block the serotonin transporter on the pre-synaptic neuron, increasing the serotonin available to bind to the post-synaptic 5-HT receptors.
  • SSRIs have very weak affinity for other mono-amine transporters (norepinephrine and dopamine reuptake).


SSRIs and Sleep