Preparation for Child Psych PRITE and Boards
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| + | * Non-responders to citalopram (Ci) (n=58 alone were randomized to '''Ci+Bupropion ER''' and '''Ci+Buspirone''' | ||
Revision as of 15:44, 14 February 2013
Introduction
- Selective serotonin reuptake inhibitors (SSRIs) block the serotonin transporter on the pre-synaptic neuron, increasing the serotonin available to bind to the post-synaptic 5-HT receptors.
- SSRIs have very weak affinity for other mono-amine transporters (norepinephrine and dopamine reuptake).
SSRIs and Sleep
Major Studies
STAR*D
- Non-responders to citalopram (Ci) (n=58 alone were randomized to Ci+Bupropion ER and Ci+Buspirone