Preparation for Child Psych PRITE and Boards
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General overview of depression can be found in the main article.
 
General overview of depression can be found in the main article.
  
==Epidemiology==
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==Epidemiology and Risk==
 
* The incidence of MDD during pregnancy is 7.5%, while period prevalence is 12.7%.
 
* The incidence of MDD during pregnancy is 7.5%, while period prevalence is 12.7%.
 
* Depression during pregnancy is associated with increased risk of pre-term birth and low birth-weight ([http://www.ncbi.nlm.nih.gov/pubmed/20921117 Meta-analysis], Grote 2010)
 
* Depression during pregnancy is associated with increased risk of pre-term birth and low birth-weight ([http://www.ncbi.nlm.nih.gov/pubmed/20921117 Meta-analysis], Grote 2010)
 
* Women treated with '''SSRI's''' have 2-3x greater risk for preterm birth and delivering low-birth-weight infants, compared to women not treated with SSRIs.  
 
* Women treated with '''SSRI's''' have 2-3x greater risk for preterm birth and delivering low-birth-weight infants, compared to women not treated with SSRIs.  
 
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* Despite in-utero SSRI exposure, there was no effect in infant growth at 12-mo in a prospective observational [http://www.ncbi.nlm.nih.gov/pubmed/23511234 study]
 
==Treatment==
 
==Treatment==
  
 
==References==
 
==References==
 
   
 
   
[http://www.ncbi.nlm.nih.gov/pubmed/20921117] Groto NK. et.al. A meta-analysis of depression during pregnancy and the risk of preterm birth, low birth weight, and intrauterine growth restriction. Arch Gen Psychiatry. 2010 Oct;67(10):1012-24
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[http://www.ncbi.nlm.nih.gov/pubmed/20921117] Groto NK, et.al. A meta-analysis of depression during pregnancy and the risk of preterm birth, low birth weight, and intrauterine growth restriction. Arch Gen Psychiatry. 2010 Oct;67(10):1012-24
 
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[http://www.ncbi.nlm.nih.gov/pubmed/23511234] Wisner KL, et.al. Does Fetal Exposure to SSRIs or Maternal Depression Impact Infant Growth? Am J Psychiatry. 2013 May 1;170(5):485-93.
  
  
 
[[Category:Disorders]]
 
[[Category:Disorders]]
 
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Revision as of 05:28, 5 May 2013

Introduction

General overview of depression can be found in the main article.

Epidemiology and Risk

  • The incidence of MDD during pregnancy is 7.5%, while period prevalence is 12.7%.
  • Depression during pregnancy is associated with increased risk of pre-term birth and low birth-weight (Meta-analysis, Grote 2010)
  • Women treated with SSRI's have 2-3x greater risk for preterm birth and delivering low-birth-weight infants, compared to women not treated with SSRIs.
  • Despite in-utero SSRI exposure, there was no effect in infant growth at 12-mo in a prospective observational study

Treatment

References

[1] Groto NK, et.al. A meta-analysis of depression during pregnancy and the risk of preterm birth, low birth weight, and intrauterine growth restriction. Arch Gen Psychiatry. 2010 Oct;67(10):1012-24 [2] Wisner KL, et.al. Does Fetal Exposure to SSRIs or Maternal Depression Impact Infant Growth? Am J Psychiatry. 2013 May 1;170(5):485-93.